Cystathionine beta-synthase. Diverts homocysteine to transsulfuration pathway for glutathione production.
Key Information
- Requires
- B6, Heme
- Produces
- Cystathionine → Cysteine → Glutathione
- Upregulation
- Can cause sulfur intolerance
- Cofactors
- Requires B6, influenced by heme
- Function
- Bridges methylation to sulfur/glutathione pathways
Connected Pathways
Homocysteine
MethylationMethylation cycle intermediate. Elevated levels indicate methylation issues or B vitamin deficiencies.
Glutathione
DetoxificationMaster antioxidant. Tripeptide of glutamate, cysteine, and glycine. Critical for detoxification and redox balance.
Sulfites
DetoxificationIntermediate sulfur compounds that must be converted to sulfates by SUOX enzyme.
