Diamine oxidase. Primary enzyme for histamine breakdown in gut.
Key Information
- Requires
- Copper, B6, Vitamin C
- Produced In
- Small intestine
- Low Causes
- Histamine intolerance
- Inhibited By
- Alcohol, Some medications
- Cofactors
- Copper, B6, B2
- Location
- Intestinal mucosa, kidney, placenta
- Deficiency
- Histamine intolerance, food reactions
Connected Pathways
Histamine
NeurotransmittersNeurotransmitter and immune mediator. Involved in allergic responses and stomach acid production.
Copper
MineralsRequired for iron metabolism, connective tissue, and neurotransmitter production. Must be balanced with zinc.
B6
B VitaminsPyridoxine. Essential for transsulfuration, neurotransmitter synthesis, and over 100 enzyme reactions.
