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Hypothalamic-pituitary-adrenal axis. Central stress response system.

Key Information

Pathway
Hypothalamus → Pituitary → Adrenals
Produces
Cortisol, DHEA, Adrenaline
Dysregulation
Chronic stress, Adrenal fatigue
Affects
Sleep, Immunity, Metabolism, Mood

Connected Pathways

Cortisol

Hormones

Primary stress hormone produced by adrenal glands. Regulates metabolism, immune function, and stress response.

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