Skip to content Skip to footer
Pathway Map
Pathway Map
Close

Signaling molecule for vasodilation and immune function. Requires BH4 for production.

Key Information

Produced By
NOS enzymes
Requires
BH4, Arginine
Dysfunction
Cardiovascular issues, Immune problems
Synthesis
Arginine + BH4 → NO (via NOS enzymes)

Connected Pathways

BH4

Cofactors

Tetrahydrobiopterin. See Biopterin entry for full details.

NOS

Enzymes

Nitric oxide synthase. Produces nitric oxide for vasodilation.

Peroxynitrite (ONOO-)

Metabolites

Highly reactive oxidant formed from nitric oxide and superoxide. Causes protein nitration and lipid peroxidation.

Complex IV

Processes

Cytochrome c oxidase - final complex of electron transport chain. Inhibited by nitric oxide.

Sunlight

Environmental

Full spectrum light essential for vitamin D synthesis, circadian rhythm, dopamine production.

Arginine

Amino Acids

Semi-essential amino acid for nitric oxide, creatine, and urea cycle.

Hydroxocobalamin

Nutrient Forms

Natural B12 form. Good for detox, longer-lasting than cyano.

0Likes
About Author

You May Also Like

GNMT
SUOX

Pathwaymap.com is my attempt at connecting my understanding with the data available. I am trying to keep my bias out of what I write on this site. But this actually introduces a problem I am still trying to solve. Some of the data refers to folic acid or methylfolate, and I do not agree with either, but there is more to this story that requires explaining. This is just one example. If you continue following my content you will likely hear me explain these various details along the way.

This is all about what you think, and I am attempting to provide you with better tools to figure out what to think.

I share a lot of short videos on my Facebook wall  https://www.facebook.com/micah.john.coffey and I often share the following videos which I think can help anyone increase their understanding of what we’re going for, even if they are still a little overwhelming.

I figured out how nutrients work and its kinda neat youtube.com/watch?v=0J8Qt6GC6FE

We’re doing it wrong  youtube.com/watch?v=qAxodqhpEkA

My old factory video from before I learned how to complicate this youtube.com/watch?v=0I3dWYbQpX4

If you are interested in iodine whyiodine.com

If you are trying to sort out the genetics situation methylate.me

Log in to track your journey