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Pathway Map
Pathway Map
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NAD+-dependent deacetylases. Regulate metabolism, aging, stress resistance.

Key Information

Types
SIRT1-7 with different locations/functions
Activation
NAD+, resveratrol, caloric restriction
Functions
DNA repair, mitochondrial biogenesis, inflammation reduction

Connected Pathways

NAD+

Cofactors

Nicotinamide adenine dinucleotide. Essential coenzyme for energy production and DNA repair.

Resveratrol

Compounds

Polyphenol activating sirtuins. Anti-aging and cardioprotective.

Mitophagy

Processes

Selective autophagy of damaged mitochondria. Critical for cellular energy.

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Pathwaymap.com is my attempt at connecting my understanding with the data available. I am trying to keep my bias out of what I write on this site. But this actually introduces a problem I am still trying to solve. Some of the data refers to folic acid or methylfolate, and I do not agree with either, but there is more to this story that requires explaining. This is just one example. If you continue following my content you will likely hear me explain these various details along the way.

This is all about what you think, and I am attempting to provide you with better tools to figure out what to think.

I share a lot of short videos on my Facebook wall  https://www.facebook.com/micah.john.coffey and I often share the following videos which I think can help anyone increase their understanding of what we’re going for, even if they are still a little overwhelming.

I figured out how nutrients work and its kinda neat youtube.com/watch?v=0J8Qt6GC6FE

We’re doing it wrong  youtube.com/watch?v=qAxodqhpEkA

My old factory video from before I learned how to complicate this youtube.com/watch?v=0I3dWYbQpX4

If you are interested in iodine whyiodine.com

If you are trying to sort out the genetics situation methylate.me

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