ConditionCardiovascular

Heart Disease

The world's leading cause of death. Heart disease encompasses coronary artery disease, heart failure, and other cardiac conditions. Driven largely by inflammation, metabolic dysfunction, and lifestyle. Highly preventable with the right approach.

Heart disease pathways
#1
Cause of Death
697K
US Deaths/Year
48%
Adults Have It
80%
Preventable

Types of Heart Disease

Coronary Artery Disease

Plaque buildup in heart arteries. Most common type. Leads to heart attacks.

Heart Failure

Heart can't pump efficiently. Progressive condition. Fluid buildup.

Arrhythmias

Abnormal heart rhythms. AFib most common. Can cause stroke.

Valve Disease

Heart valves don't work properly. Stenosis or regurgitation. May need repair.

Cardiomyopathy

Heart muscle disease. Weakened or thickened. Various causes.

Peripheral Artery Disease

Narrowed arteries elsewhere. Indicates systemic disease. Same risk factors.

Root Causes

Inflammation

  • Chronic inflammation: Damages vessel walls
  • Oxidized LDL: Gets into damaged areas
  • Immune response: Creates plaque
  • CRP marker: Predicts events

Metabolic Dysfunction

  • Insulin resistance: Drives inflammation
  • High blood sugar: Damages vessels
  • Metabolic syndrome: Cluster of risks
  • Visceral fat: Pro-inflammatory

Beyond Simple Cholesterol

LDL Particle Number

More predictive than LDL-C. Number of particles matters. ApoB is marker.

LDL Particle Size

Small, dense LDL more dangerous. Pattern B problematic. Driven by carbs.

Triglyceride/HDL Ratio

Better predictor than LDL. Under 2 is good. Reflects insulin sensitivity.

Lipoprotein(a)

Genetic risk factor. Often overlooked. Ask for this test.

Oxidized LDL

The actually dangerous form. Created by inflammation. Antioxidants help.

hs-CRP

Inflammation marker. Under 1 is optimal. Independent predictor.

Heart-Protective Nutrients

Omega-3 Fatty Acids

Anti-inflammatory. Reduce triglycerides. Stabilize heart rhythm. 2-4g daily.

CoQ10

Heart energy production. Essential with statins. 100-300mg daily.

Magnesium

Heart rhythm. Blood pressure. Vessel relaxation. Most are deficient.

Vitamin K2

Keeps calcium out of arteries. Works with D3. MK-7 form preferred.

Vitamin D

Low levels linked to heart disease. Optimize to 50-70 ng/mL. Take with K2.

Potassium

Blood pressure regulation. Balances sodium. Most don't get enough.

Prevention Strategies

Mediterranean Diet

Best-studied diet for heart. Olive oil, fish, vegetables. Reduces events 30%.

Exercise

150+ min/week. Both cardio and strength. Improves all risk factors.

Blood Sugar Control

Reduce refined carbs. Keep fasting glucose under 90. Prevent insulin resistance.

Stress Management

Chronic stress increases risk. Meditation, sleep. Cortisol management.

Quit Smoking

Single most impactful change. Risk drops immediately. Normal after 15 years.

Sleep Optimization

7-9 hours. Treat sleep apnea. Poor sleep increases CVD risk significantly.

Heart Disease Discussion