Trace MineralBrain Health

Lithium

The mood mineral. Lithium is a naturally occurring trace element with profound effects on brain health. High-dose prescription lithium treats bipolar disorder. Low-dose lithium orotate is used for mood support, neuroprotection, and has associations with longevity.

Lithium benefits
Trace
Element
1-5mg
Low-Dose Range
Orotate
OTC Form
BDNF
Increases

How Lithium Works

BDNF Increase

Boosts brain-derived neurotrophic factor. Neuroplasticity. New brain cell growth.

GSK-3 Inhibition

Glycogen synthase kinase-3. Neuroprotective. Anti-inflammatory in brain.

B12 Transport

Lithium may help B12 enter cells. Especially brain cells. Synergistic effect.

Low-Dose Benefits

Mood Stability

Evens out mood swings. Reduces irritability. Subtle stabilizing effect.

Neuroprotection

Protects brain cells. May slow neurodegeneration. Alzheimer's research.

Longevity

Areas with lithium in water have longer lifespans. Correlation studies.

Impulse Control

Reduces impulsivity. Linked to lower suicide rates in areas with lithium water.

Anxiety

Calming effect. Reduces racing thoughts. Takes edge off anxiety.

Sleep

May improve sleep quality. Circadian rhythm support. Calming.

Practical Use

Lithium Orotate

OTC form. 5mg provides ~1mg elemental lithium. Well-tolerated.

Dosing

1-5mg elemental typical. Start low. Can take with or without food.

vs Prescription

Prescription is 300-1200mg. 100x higher. Different use case. Monitor thyroid/kidneys.

Lithium Discussion