Amino AcidBCAA

Valine

The third BCAA. Valine is one of the three branched-chain amino acids, alongside leucine and isoleucine. While less researched individually, valine plays important roles in muscle maintenance, energy production, and interestingly, mental alertness—by competing with tryptophan for brain entry, it can affect serotonin levels and fatigue perception.

Valine metabolic pathways
Essential
Status
BCAA
Category
Trp
Competes With
2:1:1
BCAA Ratio

Key Functions

Muscle Maintenance

Provides nitrogen for muscle tissue. Helps prevent muscle breakdown during exercise or fasting.

Energy Production

Metabolized in muscle for ATP. Can serve as direct fuel during prolonged exercise.

Mental Alertness

Competes with tryptophan for brain entry. May reduce exercise-induced mental fatigue.

Nervous System

Important for proper nerve function and coordination. May help with tremors.

Tissue Repair

Supports wound healing and tissue regeneration. Important post-injury or surgery.

Blood Sugar

May help maintain stable blood glucose levels. Less potent than isoleucine for this.

The Tryptophan Connection

BCAAs (including valine) and tryptophan compete for the same transporter across the blood-brain barrier:

High BCAAs → Less Tryptophan in Brain

Less serotonin made. May reduce perception of fatigue during exercise. Can feel more alert.

Low BCAAs → More Tryptophan in Brain

More serotonin made. May feel sleepy or fatigued. This is why carb-heavy meals cause drowsiness.

Food Sources

Animal Sources

Meat, poultry, fish, eggs, dairy. All animal proteins are complete with good valine content.

Plant Sources

Soy, beans, lentils, peanuts, mushrooms. Combine varied plant proteins for complete profile.

Valine Discussion