Amino AcidEssential

Lysine

The collagen builder. Lysine is an essential amino acid—you must get it from food. It's critical for collagen synthesis (skin, tendons, bones), carnitine production (fat burning), calcium absorption, and immune function. Lysine is famous for fighting cold sores by competing with arginine, which viruses need.

Lysine metabolic pathways
1-3g
Daily Need
Essential
Must Eat It
Meat
Best Source
HSV
Antiviral

Key Functions

Collagen Synthesis

Essential for making collagen. Without lysine, collagen can't be properly formed or crosslinked.

Carnitine Production

Lysine + methionine → carnitine. Carnitine shuttles fatty acids into mitochondria for energy.

Calcium Absorption

Helps body absorb and retain calcium. Important for bone health. Reduces calcium loss in urine.

Antiviral (Herpes)

Competes with arginine for transport. HSV needs arginine to replicate. High lysine inhibits outbreaks.

Immune Function

Needed for antibody production. Supports immune cell function. Wound healing.

Growth Hormone

May support growth hormone release. Often combined with arginine for this purpose.

Food Sources

High Lysine Foods

  • Red meat: Beef, lamb (highest)
  • Poultry: Chicken, turkey
  • Fish: Cod, sardines, tuna
  • Dairy: Cheese, yogurt, milk
  • Eggs: Complete protein
  • Legumes: Beans, lentils (for vegetarians)

Low Lysine (High Arginine)

  • Nuts: Almonds, walnuts, peanuts
  • Seeds: Sesame, sunflower
  • Chocolate: Cacao is high arginine
  • Grains: Wheat is limiting in lysine
  • Gelatin: Surprisingly low in lysine

The Lysine:Arginine Ratio

For Cold Sore Prevention

Keep lysine higher than arginine. Avoid arginine-rich foods during outbreaks. Supplement lysine if needed.

Supplementing

500-1000mg daily preventive. Up to 3000mg during active outbreak. Take away from arginine foods.

Lysine Discussion