NADH
The energy carrier. NADH is the reduced, electron-rich form of NAD+. It carries electrons to the mitochondria to drive ATP production. Supplemental NADH is used for chronic fatigue, jet lag, and cognitive support. The final step in converting food to energy.
How NADH Works
Electron Carrier
NADH carries electrons from food breakdown to mitochondria. High-energy shuttle.
ATP Production
Electron transport chain uses NADH. Each NADH makes ~2.5 ATP. Energy currency.
NAD+/NADH Ratio
Balance matters. Too much NADH can slow processes. Cycling is normal.
Supplemental Uses
Chronic Fatigue
CFS/ME studies show benefit. Improves energy. 10mg doses used.
Jet Lag
Helps reset energy cycles. Take on arrival. Reduces fatigue.
Cognitive Function
Brain is energy-intensive. NADH supports dopamine synthesis. Focus, alertness.
Athletic Performance
Some athletes use for energy. Mitochondrial support. Mixed research.
Depression
Dopamine connection. Some studies show mood benefit. Energy for brain function.
Parkinson's
Dopamine support. Mitochondrial dysfunction in PD. Adjunctive use studied.
Practical Considerations
Sublingual Best
Absorbs under tongue. Bypasses digestion. More bioavailable.
Empty Stomach
Take 30 min before food. Morning usually best. Energizing.
Stability Issues
NADH degrades easily. Stabilized forms important. Store properly.