Vitamin K2
The calcium director. Vitamin K2 tells calcium where to go—into bones and teeth, not arteries and soft tissues. It activates proteins that bind calcium in the right places. Essential partner to vitamin D. Without K2, high-dose D may calcify arteries.
How K2 Works
Osteocalcin Activation
K2 carboxylates osteocalcin. This protein binds calcium to bone matrix. Without K2, it's inactive.
MGP Activation
Matrix GLA Protein prevents arterial calcification. K2-dependent. Keeps arteries flexible.
D3 Synergy
D3 increases calcium absorption. K2 directs it. Take together for optimal effect.
K2 Forms
MK-4
Short half-life (hours). From animal foods. High doses needed (15-45mg). Good for bones.
MK-7
Long half-life (days). From fermented foods. Lower doses work (100-200mcg). Most popular.
MK-4 + MK-7
Some products combine both. Different tissue targets. May be optimal approach.
Benefits
Bone Density
Increases bone mineral density. Reduces fracture risk. Studies show significant benefit.
Arterial Health
Prevents and may reverse calcification. Rotterdam study: 50% reduction in CV death.
Dental Health
Activator X (Weston Price). Remineralizes teeth. Prevents cavities. Jaw development.
Brain Health
Prevents brain calcification. Supports myelin. Emerging research area.
Kidney Protection
Prevents kidney stone calcium. Especially important with D supplementation.
Insulin Sensitivity
Osteocalcin affects blood sugar. K2 may improve insulin sensitivity. Research ongoing.