PathwayBiological Rhythm

Circadian Rhythm

Your body's master clock. The circadian rhythm is a 24-hour cycle controlling sleep, hormone release, metabolism, cellular repair, and immune function. Every cell has its own clock, synchronized by light and meal timing. Disruption is linked to obesity, diabetes, cancer, and mental illness.

Circadian rhythm cycle
24.2h
Natural Cycle
SCN
Master Clock
Light
Primary Signal
All Cells
Have Clocks

The Daily Rhythm

Morning (6-10am)

Cortisol peaks. Melatonin drops. Blood pressure rises. Alertness increases. Best time for light exposure.

Midday (10am-2pm)

Peak alertness. Best coordination. Highest reaction time. Cognitive performance peak.

Afternoon (2-6pm)

Best cardiovascular performance. Highest muscle strength. Body temperature peaks.

Night (10pm-6am)

Melatonin rises. Growth hormone peaks. Cellular repair. Memory consolidation. Temperature drops.

Zeitgebers (Time-Givers)

Light Exposure

Most powerful. Morning bright light sets clock. Evening blue light disrupts. Eyes send signal to SCN.

Meal Timing

Peripheral clocks sync to food. Eating at night disrupts rhythm. Time-restricted eating helps.

Exercise

Morning exercise strengthens rhythm. Late exercise can delay sleep. Consistency matters.

Social Interaction

Human contact influences rhythm. Schedules, routines. Isolation disrupts.

Temperature

Body temp fluctuates 24h. Cool environment promotes sleep. Sauna/cold exposure timing.

Sleep Schedule

Consistent bed/wake times. Even on weekends. Social jet lag harms health.

Consequences of Disruption

Metabolic Disease

Shift work increases diabetes risk 40%. Obesity link. Insulin resistance. Meal timing matters.

Cancer Risk

Night shift = WHO carcinogen. Melatonin suppression. DNA repair impaired. Breast cancer link.

Mental Health

Depression, bipolar, anxiety. Sleep-wake disruption. Light therapy helps. Rhythm restoration.

Cardiovascular

Blood pressure dysregulation. Heart attack timing. Shift work increases risk.

Immune Function

Immune cells are rhythmic. Disruption = poor defense. Vaccine timing matters. Inflammation increases.

Cognitive Decline

Memory consolidation during sleep. Alzheimer's risk. Glymphatic cleaning at night.

Optimizing Circadian Health

Morning Light

Get bright light within 30-60 min of waking. 10+ minutes outside. Light box if needed.

Evening Dim

Dim lights 2-3 hours before bed. Blue-blocking glasses. Red/amber lighting.

Consistent Schedule

Same sleep/wake daily. Weekend consistency. Avoid "social jet lag."

Time-Restricted Eating

Eat during daylight hours. 10-12 hour window. No late-night eating. Breakfast matters.

Exercise Timing

Morning or early afternoon best. Avoid vigorous exercise 3h before bed. Consistency key.

Cool Sleeping Environment

65-68°F optimal. Body temp must drop. Hot shower before bed (then cool).

Circadian Rhythm Discussion