Your genes aren't your destiny.
Explore what genes actually do, which patterns they belong to, and why expression matters more than variants.
"Genes don't cause outcomes. They reveal where the system is already under pressure."
Browse by condition.
Looking for genes associated with a specific condition? These pages show you what's involved—and why genes alone don't tell the whole story.
Anxiety
COMT, MAO-A, BDNF, and others. Why some people's nervous systems run hot—and what actually helps.
Heart Disease
APOE, MTHFR, LPA, and lipid genes. The genetic factors in cardiovascular risk—and what you can actually change.
Alzheimer's
APOE4 gets all the attention, but there's more to the story. Genes involved in brain lipid transport and clearance.
Detoxification
Phase I, II, and III detox genes. Why some people are more sensitive to chemicals, medications, and environmental toxins.
Prostate Cancer
BRCA2, HOXB13, and androgen pathway genes. Risk factors and the genes that affect hormone metabolism.
ADHD
Dopamine transporter and receptor genes. The genetics of attention, focus, and why stimulants work for some.
Diabetes
TCF7L2, PPARG, and insulin pathway genes. Genetic factors in blood sugar regulation and metabolic flexibility.
Obesity
FTO, MC4R, and appetite regulation genes. Why weight management is harder for some—and what actually matters.
Hormone Balance
CYP19A1, ESR1, and hormone metabolism genes. How your body makes, uses, and clears hormones.
Parkinson's
LRRK2, SNCA, and dopamine pathway genes. The genetics behind movement disorders and neurodegeneration.
Browse by pattern.
Multiple genes often share the same underlying pattern. Understanding patterns is more useful than memorizing genes.
Slow Clearance
COMT, GST, CYP issues—things don't clear as fast
Fragile Methyl Buffering
MTHFR, MTR, MTRR—methylation under pressure
High Oxidative Load
GST, SOD, catalase—oxidative stress management
Poor Fat-Soluble Handling
APOE, BCMO1—issues with fat-based nutrients
Low Bile Throughput
UGT1A1, ABCB4—sluggish bile and toxin clearance
Popular genes.
MTHFR
Methylation & FolateAffects how you process folate. Common variants reduce function, but it's not your genetic destiny.
COMT
Dopamine & StressClears dopamine and norepinephrine. Determines if you're a 'worrier' or a 'warrior.'
APOE
Lipids & Brain HealthTransports fats and clears brain debris. APOE4 increases risk—but it's not destiny.
MTHFR + COMT
The InteractionHow these two methylation genes interact and compete for resources.
How to use this section.
Find the gene
Start with the gene you're curious about. We cover what it actually does, not just what variant you have.
Follow the pathway
Every gene page links to the enzymes, nutrients, and pathways it connects to. The gene is just the entry point.
See the patterns
Multiple genes often share the same underlying pattern. Understanding patterns is more useful than memorizing genes.
Focus on expression
Having a variant doesn't mean it's active. Environment, nutrients, and lifestyle determine expression.
Ready to go deeper?
Start with a gene you're curious about, then follow the connections to understand the full picture.