Prefrontal Cortex
The brain's CEO. The prefrontal cortex (PFC) sits behind your forehead and is the most evolved part of the human brain. It handles executive functions: planning, decision-making, impulse control, working memory, and complex reasoning. It's the last brain region to fully develop (around age 25) and is highly sensitive to stress, sleep deprivation, and substances. ADHD involves PFC underactivity.

PFC Functions
Planning
Future thinking. Goal setting. Strategy formation. Multi-step tasks.
Decision Making
Weighing options. Risk assessment. Value judgments. Complex choices.
Impulse Control
Inhibiting responses. Self-regulation. Delaying gratification. "Brakes."
Working Memory
Holding info temporarily. Mental manipulation. Following instructions.
Attention Control
Focus direction. Filtering distractions. Task switching.
Social Cognition
Theory of mind. Social judgment. Emotional regulation. Personality.
What Impairs the PFC
Stress
Cortisol impairs function. "Amygdala hijack." Poor decisions under stress.
Sleep Deprivation
PFC very sleep-sensitive. Impulsivity increases. Decision quality drops.
Alcohol
First area affected. Explains lowered inhibitions. Impaired judgment.
Chronic Inflammation
Brain fog connection. Cytokines affect function. Diet and lifestyle matter.
Low Blood Sugar
PFC is glucose-hungry. "Hangry" phenomenon. Ego depletion theory.
Teen Brain
Still developing until ~25. Risk-taking explained. Limbic system leads.
Strengthening the PFC
Meditation
Increases gray matter in PFC. Improves attention. Regular practice shows changes.
Exercise
Increases BDNF. Improves executive function. Acute and chronic benefits.
Sleep
Restores PFC function. Priority for decisions. 7-9 hours.
Novel Learning
Challenges create growth. New skills. Cognitive reserve building.