Vitamin B6
The versatile B. Pyridoxine (B6) is involved in over 100 enzyme reactions. It's essential for making neurotransmitters like serotonin and dopamine, metabolizing protein, and supporting immune function. Critical for histamine breakdown via DAO enzyme.
Key Functions
Neurotransmitters
Makes serotonin, dopamine, GABA. Mood, sleep, calm. Low B6 = low neurotransmitters.
Histamine Breakdown
DAO enzyme requires B6. Histamine intolerance link. Critical for mast cell issues.
Protein Metabolism
Amino acid conversions. The more protein you eat, the more B6 you need.
Benefits & Uses
PMS Support
Reduces mood swings, bloating. Well-studied for PMS. 50-100mg effective.
Morning Sickness
First-line treatment for nausea in pregnancy. 25-50mg safe and effective.
Carpal Tunnel
May reduce symptoms. Nerve health support. Often tried before surgery.
Homocysteine
Works with B12 and folate. Cardiovascular protection. Methylation support.
Dream Recall
Increases dream vividness. Acetylcholine connection. Take before bed.
Immune Function
T-cell production. Antibody synthesis. Deficiency impairs immunity.
Forms & Cautions
P5P (Active Form)
Pyridoxal-5-phosphate. No conversion needed. Better for some people.
Pyridoxine HCl
Common form. Needs liver conversion. Usually works fine.
Toxicity Risk
High doses (200mg+) long-term can cause neuropathy. Tingling, numbness. Reversible.