Endocrine

Adrenal Health

Your stress response command center. The adrenal glands sit atop your kidneys, producing cortisol, adrenaline, and DHEA. Modern life is burning them out.

Adrenal glands and stress response
50+
Hormones Made
AM
Cortisol Peak
HPA
Axis
Vit C
Highest in Body

What Your Adrenals Do

Cortex (Outer)

  • Cortisol: Stress response, blood sugar, immune regulation
  • Aldosterone: Sodium/potassium balance, blood pressure
  • DHEA: Precursor to sex hormones, anti-aging

Medulla (Inner)

  • Adrenaline (Epinephrine): Fight-or-flight, rapid stress response
  • Noradrenaline: Alertness, focus, blood pressure

The HPA Axis: Your Stress System

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Hypothalamus

Detects stress, releases CRH (corticotropin-releasing hormone)

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Pituitary

Responds by releasing ACTH (adrenocorticotropic hormone)

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Adrenal

ACTH signals adrenals to produce cortisol and adrenaline

When cortisol rises, it signals the hypothalamus to stop—negative feedback loop. Chronic stress breaks this loop.

⚠️ Stages of Adrenal Dysfunction

"Adrenal fatigue" isn't recognized by mainstream medicine, but HPA axis dysregulation is real. Here's how chronic stress progressively damages the system:

Stage 1: Alarm

  • • Cortisol surges high
  • • Feel wired, anxious
  • • Trouble sleeping
  • • Weight gain (especially belly)
  • • High energy, but unsustainable

Stage 2: Resistance

  • • Cortisol starts dropping
  • • DHEA declining
  • • Tired but wired
  • • Afternoon energy crashes
  • • Need caffeine/sugar to function

Stage 3: Exhaustion

  • • Cortisol flatlined low
  • • DHEA depleted
  • • Profound fatigue
  • • Can't handle any stress
  • • Multiple system dysfunction

Signs of Adrenal Dysfunction

Energy

  • • Fatigue that sleep doesn't fix
  • • Afternoon crashes (2-4pm)
  • • Second wind at night
  • • Slow to start in morning

Sleep

  • • Trouble falling asleep
  • • Waking 2-4am
  • • Unrefreshing sleep
  • • Need alarm to wake up

Cravings

  • • Salt cravings
  • • Sugar/caffeine dependence
  • • Carb cravings

Stress Response

  • • Low stress tolerance
  • • Easily overwhelmed
  • • Slow recovery from illness

Blood Pressure

  • • Low blood pressure
  • • Dizziness on standing
  • • Light-headed

Other

  • • Brain fog
  • • Low libido
  • • Allergies worsening

âś… Supporting Adrenal Health

Reduce Stressors

Can't supplement your way out of chronic stress. Address root causes first.

Sleep Hygiene

In bed by 10pm. Adrenals repair during sleep. No screens before bed.

Blood Sugar Stability

Every blood sugar crash triggers cortisol. Protein with every meal. Avoid sugar.

Vitamin C

Adrenals have highest concentration in body. Depleted rapidly by stress. 1-3g daily.

Magnesium

Anti-stress mineral. Depleted by cortisol. Most people need supplementation.

B Vitamins

Especially B5 (pantothenic acid) and B6. Essential for adrenal hormone production.

Adaptogens

Ashwagandha, rhodiola, eleuthero help modulate stress response.

Salt

Low aldosterone = salt cravings. Quality sea salt may help if craving salt.

Morning Sunlight

Sets cortisol rhythm. 10-20 minutes of morning sun helps normalize HPA axis.

đź§Ş Testing Adrenal Function

4-Point Cortisol Test

Saliva cortisol at 4 times throughout the day. Shows the rhythm, not just a single point. Should be highest in morning, lowest at night.

DUTCH Test

Comprehensive hormone test including cortisol metabolites, cortisone, and cortisol rhythm. More detailed than saliva testing.

DHEA-S Blood Test

DHEA-S is an adrenal marker. Low levels suggest adrenal insufficiency or chronic stress.

Morning Cortisol

Blood cortisol at 8am. Less useful alone but can indicate severe dysfunction if very low.

Adrenal Health Discussion