Symptom

Anxiety isn't a character flaw.

It's a signal that something in your biochemistry needs attention.

Anxiety pathway diagram

What's happening in your brain

Anxiety involves real changes in brain function and chemistry. It's not weakness—it's biology.

1

Overactive amygdala

Your brain's fear center fires too easily, seeing threats where there aren't any.

2

Underactive prefrontal cortex

The rational part of your brain can't override the fear signals effectively.

3

HPA axis dysregulation

Your stress response system is stuck in overdrive, pumping out cortisol.

4

Neurotransmitter imbalance

Low GABA, serotonin problems, too much norepinephrine and glutamate.

90%

of your serotonin is made in your gut, not your brain.

This is why digestive issues and anxiety often go together.

Genetic Factors

Some people are wired for it.

COMT variants (slow)

People with slow COMT clear stress hormones (dopamine, norepinephrine, adrenaline) more slowly. This means anxiety and stress linger longer. The upside? Often better focus and memory.

GAD1 variants

Variations in the gene that makes the enzyme for GABA synthesis. Can reduce your brain's ability to produce calming neurotransmitters.

Where to start.

Check nutrient status. Especially magnesium, B vitamins, zinc, vitamin D, and omega-3s.

Stabilize blood sugar. Track how you feel 2-3 hours after meals. Crashes cause anxiety.

Fix sleep first. Anxiety and poor sleep feed each other. Break the cycle.

Try eliminating caffeine. Just for 2 weeks. See what happens.

Get a full thyroid panel. Not just TSH. Include T3, T4, and antibodies.

Explore the connections.

Anxiety doesn't exist in isolation. See how it connects to other pathways.

Anxiety Discussion